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Published in United States of America - Social interactions and entertainment - 18 Feb 2022 21:58 - 0
Basic Biology Research:
DARPA is interested in fundamental and applied research in the biological sciences across all scales (e.g., quantum to ecological) to contribute to defense capabilities including development of synergies with other disciplines (e.g., information technology, micro/nanotechnology, manufacturing). While broad in scope, novel approaches to biomedical applications, biological warfare defense, and human performance optimization are of particular interest. Specific areas of interest include, but are not limited to:
• Technologies to engineer field medical therapies at the point of care, such as production of multiple drugs from a single pro-drug, or to adapt therapies for wide variations in body m, metabolism, or physiologic stress
• Technologies for non-invasive and/or remote essment of physiological status (e.g., vital signs, blood chemistry)
• Unique approaches for pre-symptomatic diagnosis of disease and health
• Bioelectronic and biophotonic interfaces (e.g., non-fouling implantable chemical and neural sensors)
• Devices for rapid synthesis and molecular analysis and real-time measurement and characterization of biomolecules and other biological structures
• Novel approaches for discovering unidentified microbes
• Bioprospecting, as defined as using microbial biodiversity for production of biotechnologically important products and industrial endeavors (e.g., medicine, discovery of new materials)
• Remote detection/characterization of naturally occurring or engineered biological substances
• Technologies that radically accelerate pre-clinical evaluation of the safety or efficacy of therapeutics and vaccines
• Approaches for, and technology devoted to, maintaining the general health of deployed troops
• New approaches for creating greater environmental adaptability
• Biological approaches to the growth of materials and devices
• New methods for direct manipulation and control of biomaterials (e.g., proteins) on length and temporal scales commensurate with biological processes
• Manipulation of protein conformation to maximize stability and control affinity of proteins
• New technologies to reduce the medical logistics burden in the field
• Biomolecular strategies for information processing or biological-based emitter/receiver communications including chemical signaling (e.g., olfaction) and other information transduction pathways
• Theoretical and experimental efforts supporting the understanding of intelligence and self organization in the natural world
• Theoretical and experimental efforts to understand the nature of consciousness
• Systems and components supporting the development of engineered intelligence
• Novel biomarkers whose continuous monitoring over a period of time provides real-time essment of physiological processes (such as deviation from healthy status, healing rates, etc.)
Basic Neuroscience Research:
DSO is interested in neuroscience research ideas enabling innovation in the science and technology for improved human performance, specifically to overcome the challenges encountered in the operational environment. The areas for research may span fundamental, applied, and computational neuroscience. Specific areas of interest include, but are not limited to:
• Approaches that minimize the after-effects of neurotrauma and promote faster, more complete recuperation, including penetrating and non-penetrating injuries
• Neuromorphic information processing systems and architectures, electronic devices, and robotic systems
• Environments, systems, and concepts for the evaluation of machine intelligence
• Understanding the human effects of non-lethal weapons
• Advanced signal processing techniques for the decoding of neural signals in real time, specifically those ociated with operationally relevant cognitive events, including target detection, errors, and other decision-making processes
• Novel techniques and experimental methods for understanding the impact of stress on the brain (e.g., information processing, decision making, attention, and memory) with a specific interest in translating work on animal models to human lations
• Theoretical and experimental efforts to quantitatively describe and understand complex human neuroscience as it relates to social and economic systems
• Experimental efforts to understand the capability of using neural activity to induce and regulate an intended physiologic activity
Operational Neuroscience:
DSO is interested in research aimed at the use of neuroscience tools and techniques to design systems, train individuals, and measure the cognitive state in military settings. Specific areas of interest include, but are not limited to:
• Adaptability and resilience of individuals to high stress environments
• Novel wearable neural sensors and recording technologies
• Real-time neural signal acquisition and analysis in applied environments
• Investigations into the cognitive state of warfighters during real and simulated task environments
• Novel interface and sensor designs for interacting with the central (cortical and subcortical structures) and peripheral nervous systems, with a particular emphasis on non-invasive and non-contact approaches
• New approaches for understanding and predicting the behavior of individuals and groups, especially those that elucidate the neurobiological basis of behavior and decision making
• New approaches for training individuals and teams, including embedded training and simulation
• Experimental efforts to link social cognition to issues such as group cohesion, leadership and followership, and education and training
• Understanding and improving team performance
• New approaches for improving rapid decision-making in chaotic or data-poor environments
Behavioral Neuroscience: DSO is interested in the exploration and explanation of neurobiological mechanisms that are responsible for a variety of human capabilities and which are influenced by behaviors in the virtual world, as well as the neurobiology of moral judgment, development, and action.
• Understanding attitude and habit formation, particularly when uniquely influenced by or highly plastic in response to virtual interactions
• New approaches for measuring human propensity to engage in violence against out-group members
• Understanding mechanisms important to mobilization into violent social movements and groups
• Investigations into pathologies resulting in warfighter accidents, misjudgments, and maladaptive behavior
Quantum Science and Technology:
Physics of Nano-Materials and Devices: DSO is interested in fundamental and applied research in nano-materials, design methodologies, and potential device application (e.g., navigation, communication, and sensing of chemical, biological, optical, infrared, acoustic, magnetic, and other signals of interest). Specific areas of interest include, but are not limited to:
• Nanostructured optical components enabling novel wavefront control
• Interaction of materials with their environment
• Unique material properties and capabilities available at the micro- and nanoscale
• Technologies for fabrication of particles and functional structures in the nano- and micro-to-millimeters size range, with arbitrary geometry
• Methods for precise measurement of forces and fields that lend themselves to deployment on mobile platforms (e.g., atom interferometry)
• New methods to achieve precise molecular recognition
• Integrated methods for continuous sampling of biofluids to monitor human physiological processes
.........................................................................................................................................................................................................................................
Source - DARPA RFP for DSO Defense Sciences Research and Technology
DARPA is interested in fundamental and applied research in the biological sciences across all scales (e.g., quantum to ecological) to contribute to defense capabilities including development of synergies with other disciplines (e.g., information technology, micro/nanotechnology, manufacturing). While broad in scope, novel approaches to biomedical applications, biological warfare defense, and human performance optimization are of particular interest. Specific areas of interest include, but are not limited to:
• Technologies to engineer field medical therapies at the point of care, such as production of multiple drugs from a single pro-drug, or to adapt therapies for wide variations in body m, metabolism, or physiologic stress
• Technologies for non-invasive and/or remote essment of physiological status (e.g., vital signs, blood chemistry)
• Unique approaches for pre-symptomatic diagnosis of disease and health
• Bioelectronic and biophotonic interfaces (e.g., non-fouling implantable chemical and neural sensors)
• Devices for rapid synthesis and molecular analysis and real-time measurement and characterization of biomolecules and other biological structures
• Novel approaches for discovering unidentified microbes
• Bioprospecting, as defined as using microbial biodiversity for production of biotechnologically important products and industrial endeavors (e.g., medicine, discovery of new materials)
• Remote detection/characterization of naturally occurring or engineered biological substances
• Technologies that radically accelerate pre-clinical evaluation of the safety or efficacy of therapeutics and vaccines
• Approaches for, and technology devoted to, maintaining the general health of deployed troops
• New approaches for creating greater environmental adaptability
• Biological approaches to the growth of materials and devices
• New methods for direct manipulation and control of biomaterials (e.g., proteins) on length and temporal scales commensurate with biological processes
• Manipulation of protein conformation to maximize stability and control affinity of proteins
• New technologies to reduce the medical logistics burden in the field
• Biomolecular strategies for information processing or biological-based emitter/receiver communications including chemical signaling (e.g., olfaction) and other information transduction pathways
• Theoretical and experimental efforts supporting the understanding of intelligence and self organization in the natural world
• Theoretical and experimental efforts to understand the nature of consciousness
• Systems and components supporting the development of engineered intelligence
• Novel biomarkers whose continuous monitoring over a period of time provides real-time essment of physiological processes (such as deviation from healthy status, healing rates, etc.)
Basic Neuroscience Research:
DSO is interested in neuroscience research ideas enabling innovation in the science and technology for improved human performance, specifically to overcome the challenges encountered in the operational environment. The areas for research may span fundamental, applied, and computational neuroscience. Specific areas of interest include, but are not limited to:
• Approaches that minimize the after-effects of neurotrauma and promote faster, more complete recuperation, including penetrating and non-penetrating injuries
• Neuromorphic information processing systems and architectures, electronic devices, and robotic systems
• Environments, systems, and concepts for the evaluation of machine intelligence
• Understanding the human effects of non-lethal weapons
• Advanced signal processing techniques for the decoding of neural signals in real time, specifically those ociated with operationally relevant cognitive events, including target detection, errors, and other decision-making processes
• Novel techniques and experimental methods for understanding the impact of stress on the brain (e.g., information processing, decision making, attention, and memory) with a specific interest in translating work on animal models to human lations
• Theoretical and experimental efforts to quantitatively describe and understand complex human neuroscience as it relates to social and economic systems
• Experimental efforts to understand the capability of using neural activity to induce and regulate an intended physiologic activity
Operational Neuroscience:
DSO is interested in research aimed at the use of neuroscience tools and techniques to design systems, train individuals, and measure the cognitive state in military settings. Specific areas of interest include, but are not limited to:
• Adaptability and resilience of individuals to high stress environments
• Novel wearable neural sensors and recording technologies
• Real-time neural signal acquisition and analysis in applied environments
• Investigations into the cognitive state of warfighters during real and simulated task environments
• Novel interface and sensor designs for interacting with the central (cortical and subcortical structures) and peripheral nervous systems, with a particular emphasis on non-invasive and non-contact approaches
• New approaches for understanding and predicting the behavior of individuals and groups, especially those that elucidate the neurobiological basis of behavior and decision making
• New approaches for training individuals and teams, including embedded training and simulation
• Experimental efforts to link social cognition to issues such as group cohesion, leadership and followership, and education and training
• Understanding and improving team performance
• New approaches for improving rapid decision-making in chaotic or data-poor environments
Behavioral Neuroscience: DSO is interested in the exploration and explanation of neurobiological mechanisms that are responsible for a variety of human capabilities and which are influenced by behaviors in the virtual world, as well as the neurobiology of moral judgment, development, and action.
• Understanding attitude and habit formation, particularly when uniquely influenced by or highly plastic in response to virtual interactions
• New approaches for measuring human propensity to engage in violence against out-group members
• Understanding mechanisms important to mobilization into violent social movements and groups
• Investigations into pathologies resulting in warfighter accidents, misjudgments, and maladaptive behavior
Quantum Science and Technology:
Physics of Nano-Materials and Devices: DSO is interested in fundamental and applied research in nano-materials, design methodologies, and potential device application (e.g., navigation, communication, and sensing of chemical, biological, optical, infrared, acoustic, magnetic, and other signals of interest). Specific areas of interest include, but are not limited to:
• Nanostructured optical components enabling novel wavefront control
• Interaction of materials with their environment
• Unique material properties and capabilities available at the micro- and nanoscale
• Technologies for fabrication of particles and functional structures in the nano- and micro-to-millimeters size range, with arbitrary geometry
• Methods for precise measurement of forces and fields that lend themselves to deployment on mobile platforms (e.g., atom interferometry)
• New methods to achieve precise molecular recognition
• Integrated methods for continuous sampling of biofluids to monitor human physiological processes
.........................................................................................................................................................................................................................................
Source - DARPA RFP for DSO Defense Sciences Research and Technology
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